TASTYLIA Tablets – Complete Patient Information Guide

What is TASTYLIA?

TASTYLIA is an orally disintegrating tablet containing Tadalafil, a prescription medication belonging to the class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. It is primarily prescribed for the treatment of erectile dysfunction (ED) in adult men. The unique sublingual formulation allows the tablet to dissolve on the tongue without water, offering convenience and potentially faster onset of action compared to traditional oral tablets.

TASTYLIA is available in various strengths and should only be used under proper medical supervision following a healthcare provider’s assessment and prescription.

How Does TASTYLIA Work?

TASTYLIA works by targeting a specific enzyme in the body called phosphodiesterase type 5 (PDE5). Here’s how the mechanism unfolds in simple terms:

• Enzyme Inhibition: When sexually stimulated, the body releases nitric oxide in the erectile tissue. This triggers an enzyme that produces cyclic guanosine monophosphate (cGMP), which relaxes smooth muscles and increases blood flow to the penile region.
• Enhanced Blood Flow: PDE5 normally breaks down cGMP. By inhibiting PDE5, Tadalafil allows cGMP levels to remain elevated for longer periods, promoting sustained blood flow to achieve and maintain an erection.
• Duration of Action: Tadalafil has a longer half-life compared to other PDE5 inhibitors, with effects lasting up to 36 hours in some cases, though this does not mean continuous erection—sexual stimulation is still required.

Important Note: TASTYLIA does not cause automatic erections and does not increase sexual desire. It works only in the presence of sexual arousal.

Approved Uses and Therapeutic Benefits

TASTYLIA (Tadalafil) is medically approved and prescribed for:

• Erectile Dysfunction (ED): Helping adult men achieve and maintain erections sufficient for sexual activity when sexually stimulated

• Improvement in Sexual Confidence: May reduce performance anxiety associated with ED when used as part of comprehensive treatment

• Convenient Administration: Orally disintegrating formulation eliminates the need for water, offering discretion and ease of use

• Flexible Timing: Can be taken as needed before anticipated sexual activity (timing varies by strength and individual response)

Off-Label Considerations: While Tadalafil is also approved for other conditions like benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension in different formulations and dosing regimens, TASTYLIA’s specific formulation and strength profile is primarily indicated for ED. Always consult your healthcare provider regarding appropriate use.

Dosage Guidance and Administration

General Dosing Principles:

• TASTYLIA tablets are designed to dissolve on the tongue and should not be swallowed whole, chewed, or crushed
• Place the tablet on the tongue and allow it to disintegrate completely before swallowing
• Can be taken with or without food, though high-fat meals may delay absorption
• Typically taken approximately 30 minutes to 1 hour before anticipated sexual activity
• Do not take more than one dose within a 24-hour period

Strength Variations:

TASTYLIA is available in multiple strengths (commonly 2.5mg, 5mg, 10mg, and 20mg). Your healthcare provider will determine the appropriate starting dose based on:

• Your overall health status
• Severity of erectile dysfunction
• Other medications you are taking
• Kidney or liver function
• Your response to initial treatment

Important: Dosage recommendations vary significantly among individuals. Never adjust your dose or take someone else’s medication. Always follow your healthcare provider’s specific instructions.

Potential Side Effects

Like all medications, TASTYLIA may cause side effects, though not everyone experiences them.

Common Side Effects (may affect up to 1 in 10 people):

• Headache • Flushing (warmth, redness in face, neck, or chest) • Indigestion or upset stomach • Nasal congestion • Back pain or muscle aches • Dizziness or lightheadedness • Changes in vision (blurred vision, sensitivity to light, or difficulty distinguishing between blue and green colors)

These effects are typically mild to moderate and often resolve on their own as your body adjusts to the medication.

Serious Side Effects (require immediate medical attention):

• Sudden vision loss in one or both eyes (possible sign of non-arteritic anterior ischemic optic neuropathy) • Sudden hearing decrease or loss, sometimes with ringing in the ears or dizziness • Priapism: An erection lasting more than 4 hours (medical emergency requiring immediate treatment to prevent permanent damage) • Chest pain or irregular heartbeat during or after sexual activity • Severe allergic reactions: Rash, itching, swelling (especially of face, tongue, or throat), severe dizziness, difficulty breathing • Seizures or convulsions

If you experience any serious side effects, seek emergency medical care immediately.

Comparison with Peer Medications and Other Brands

Note: This comparison is for informational purposes only. The choice between medications should be made by your healthcare provider based on your individual medical profile, preferences, and response to treatment. All medications listed require a valid prescription.

Drug Interactions and Medical Warnings

Critical Drug Interactions:

Never take TASTYLIA with:

• Nitrates (nitroglycerin, isosorbide mononitrate/dinitrate) used for chest pain—this combination can cause a dangerous drop in blood pressure • Riociguat or other guanylate cyclase stimulators used for pulmonary hypertension

Use with Caution (requires medical supervision):

• Alpha-blockers (tamsulosin, doxazosin) for prostate or blood pressure • Other blood pressure medications • HIV protease inhibitors (ritonavir, saquinavir) • Antifungal medications (ketoconazole, itraconazole) • Certain antibiotics (clarithromycin, erythromycin) • Other PDE5 inhibitors • Medications for irregular heartbeat • Rifampin and other enzyme inducers

Important Medical Warnings:

• Cardiovascular Risk: Sexual activity carries potential cardiac risk. Consult your doctor if you have heart disease, have had a heart attack or stroke within the past 6 months, have irregular heartbeat, or uncontrolled blood pressure

• Vision Problems: If you have retinitis pigmentosa or history of non-arteritic anterior ischemic optic neuropathy (NAION)

• Kidney or Liver Impairment: Dose adjustment may be necessary

• Peyronie’s Disease or Penile Deformity: Use with medical guidance

• Blood Cell Disorders: Sickle cell anemia, multiple myeloma, or leukemia

• Bleeding Disorders or Active Stomach Ulcers: Increased bleeding risk

Alcohol: Excessive alcohol consumption may increase the risk of side effects and can impair erectile function. Limit alcohol intake when using TASTYLIA.

Grapefruit: Grapefruit juice may increase Tadalafil blood levels and increase side effect risk. Avoid consuming large amounts of grapefruit or grapefruit juice.

Who Should Avoid or Use TASTYLIA with Caution?

Do NOT use TASTYLIA if you:

• Are allergic to Tadalafil or any ingredients in the formulation • Are taking nitrate medications for chest pain or heart problems • Are taking riociguat for pulmonary hypertension • Have been advised by your doctor to avoid sexual activity due to heart problems • Have severe liver disease • Have low blood pressure (hypotension) • Recently had a stroke or heart attack (within 6 months) • Have a rare hereditary eye disease like retinitis pigmentosa • Are a woman or child under 18 years of age (not approved for these populations)

Use with Caution and Medical Supervision if you have:

• Heart rhythm problems or heart disease • Kidney or liver problems • High or low blood pressure • History of priapism (prolonged erections) • Anatomical deformation of the penis • Conditions predisposing to priapism (sickle cell anemia, multiple myeloma, leukemia) • Bleeding disorders or active peptic ulcers • Vision or hearing problems • Are taking multiple medications for other conditions

Always inform your healthcare provider about your complete medical history and all medications (prescription, over-the-counter, herbal supplements) you are currently taking before starting TASTYLIA.

Storage and Handling Instructions

Proper storage ensures medication effectiveness and safety:

• Temperature: Store at room temperature between 15°C to 30°C (59°F to 86°F)

• Moisture: Keep tablets in original packaging until use. Protect from moisture and humidity

• Light: Store away from direct sunlight and heat sources

• Child Safety: Keep out of reach of children and pets

• Blister Packaging: Do not remove tablet from blister pack until immediately before use to prevent degradation

• Expiration: Check expiration date. Do not use expired medication

• Disposal: Dispose of unused or expired medication properly according to local regulations or through pharmacy take-back programs. Do not flush down toilet or throw in household trash where children or animals might access them

Frequently Asked Questions

Q1: How long before sexual activity should I take TASTYLIA?

A: TASTYLIA typically begins working within 30 to 60 minutes of administration, though individual response times may vary. Some men may notice effects sooner, especially with the orally disintegrating formulation. Your healthcare provider can advise you on optimal timing based on your specific strength and individual factors. Remember that sexual stimulation is required for the medication to work.

Q2: Can I take TASTYLIA daily, or only when needed?

A: TASTYLIA can be prescribed either “as needed” (taken before anticipated sexual activity) or as a daily low-dose regimen, depending on your prescription and treatment goals. Lower strength versions (2.5mg or 5mg) are sometimes prescribed for daily use, while higher strengths are typically used on-demand. Daily use may be recommended for men who anticipate frequent sexual activity. Never change your dosing schedule without consulting your healthcare provider.

Q3: What should I do if TASTYLIA doesn’t work the first time?

A: Several factors can affect effectiveness during initial use, including anxiety, incorrect timing, inadequate sexual stimulation, or insufficient dosing. Healthcare providers often recommend trying the medication on at least 4-6 separate occasions before concluding it’s ineffective. If you feel it’s not working after multiple appropriate attempts, contact your doctor—they may adjust your dose, suggest timing changes, or investigate underlying factors affecting erectile function. Never increase the dose on your own.

Q4: Is it safe to take TASTYLIA with alcohol?

A: While moderate alcohol consumption (1-2 standard drinks) is unlikely to cause significant problems, excessive alcohol intake can increase the risk of side effects such as dizziness, headache, low blood pressure, and can independently impair erectile function. Alcohol is a depressant that can interfere with sexual performance. It’s advisable to limit alcohol consumption when planning to use TASTYLIA and discuss your drinking habits with your healthcare provider.

Q5: What is the difference between TASTYLIA and regular Tadalafil tablets?

A: TASTYLIA is an orally disintegrating tablet (ODT) formulation of Tadalafil that dissolves on the tongue without water, while regular Tadalafil tablets are swallowed whole with water. The orally disintegrating form may offer advantages such as convenience, discretion, and potentially faster absorption for some individuals, though both contain the same active ingredient. The choice between formulations depends on patient preference and specific medical considerations as determined by your healthcare provider.

Q6: Can TASTYLIA cure erectile dysfunction permanently?

A: No. TASTYLIA is a symptomatic treatment that temporarily helps achieve and maintain erections when sexually stimulated—it does not cure the underlying causes of erectile dysfunction. ED can result from various factors including cardiovascular disease, diabetes, psychological issues, hormonal imbalances, or lifestyle factors. Effective long-term management often requires addressing these root causes through lifestyle modifications, treatment of underlying conditions, psychological counseling, or ongoing medication use as directed by your healthcare provider.

Medical and Prescription Disclaimer

Important Medical Information:

This content is provided for educational and informational purposes only and is not intended to substitute professional medical advice, diagnosis, or treatment. TASTYLIA (Tadalafil) is a prescription medication that should only be used under the supervision of a qualified healthcare provider.

Key Points:

• Always consult with a licensed physician or healthcare professional before starting, stopping, or changing any medication • This information does not cover all possible uses, directions, precautions, drug interactions, allergic reactions, or adverse effects • Individual responses to medication vary—what works for one person may not be appropriate for another • Never share your prescription medication with others, even if they have similar symptoms • Self-diagnosis and self-medication can be dangerous and are strongly discouraged • If you experience a medical emergency or serious side effect, seek immediate medical attention or call emergency services

Prescription Requirement:

TASTYLIA requires a valid prescription from a licensed healthcare provider. Online consultations, where available, should involve legitimate medical evaluation by qualified professionals. Purchasing prescription medications without a valid prescription is illegal and potentially dangerous.

Product Authenticity:

Ensure you obtain medications only from licensed, reputable pharmacies. Counterfeit medications pose serious health risks and may contain incorrect ingredients, wrong dosages, or harmful substances.

Copyright and Accuracy:

While every effort has been made to ensure the accuracy of this information, medical knowledge evolves continuously. Always refer to the most current prescribing information and consult healthcare professionals for the latest guidance specific to your situation.

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Important Reminder: Always have a valid prescription from your healthcare provider before ordering prescription medications. Consult with your doctor regarding the appropriateness of any medication for your specific health condition.

Medical Review Note: This information is current as of the publication date and is intended for patient education. For the most up-to-date prescribing information, drug interactions, and safety updates, consult official prescribing information from regulatory authorities or speak directly with healthcare professionals.